Heath Ledger's performance as The Joker has set the bar high for Gotham City villains, but reports in the US say studio bosses have set their sights on Depp as The Riddler and Philip Seymour Hoffman as The Penguin.
"Producers are convinced that the role of The Riddler is perfect for Depp. Johnny's a pro. He'll be able to take direction and still make the character his own. And what better Penguin is there than Philip Seymour Hoffman?" a source said.
They could be joining Angelina Jolie - the actress is reported to be after the role of Catwoman.
Sure, it is likely to star Christian Bale reprising his role as The Caped Crusader.